| # | Ongoing Clinical Trial | Participating Sites |
|---|---|---|
| 1 | Efficacy and safety of Punarnavadi Mandura alone and in combination with Drakshavaleha
compared to iron folic acid in the treatment of moderate iron deficiency anaemia among non-pregnant women of reproductive age group: a community-based three arm multi-centre randomized controlled trial. |
|
| 2 | A Phase-I, Open Label, Dose Escalation, Dose Expansion, Multicenter, First in Human (FIH) Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of Oral AUR107 in Patients with Relapsed Advanced Malignancies (SHAKTI-1) |
2 Phase-I sites
+
26 other sites CTRI/2023/05/052954 |
| 3 | A Multicentre, Open-Label, Single-Arm, Two- Cohort, Phase 3, Clinical Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Eliglustat Sublingual Film in Patients with Gaucher Disease Type 1 |
6 Sites CTRI/2024/08/072953 |
| 4 | A Phase-I Double Blind, Randomized, Placebo Controlled, Parallel, Multicentre, Proof-of-concept Study To Evaluate The Efficacy And Safety Of Desidustat Oral Tablet For Treatment Of Sickle Cell Disease |
5 Sites CTRI/2024/06/068363 |
| # | Critical Trial | Status | Sites |
|---|---|---|---|
| 1 | A Phase-I, Proof-of-Concept, Placebo Controlled, Randomised Trial to Investigate the Efficacy and Safery of Oxfendazole as a Macrofilaricidal Drug in Adults Harbouring Lymphatic Filarial Worms. | Approved by DCGI, to be initiated in May 2025, | |
| 2 | Efficacy and Safety of Ayurvedic package of Interventions vs Allopathic package of interventions in treatment of early knee osteoarthritis, a Phase-III randomized controlled trial | Preparatory Phase | |
| 3 | Safety and efficacy of probiotic interventions in reducing mortality, severe infection and morbidity in preterm and SGA infants. | Preparatory Phase | |
| 4 | Efficacy and safety of Bedaquiline in combination with MDT for the treatment of Multibacillary Leprosy | Preparatory Phase | |
| 5 | KFD Vaccine | Preparatory Phase |
1.PGIMER, Chandigarh, 2. ACTREC, Navi Mumbai from the Phase-I network and 26 other sites |
| 6 | Mynflu001 (a novel quadrivalent, recombinant protein subunit vaccine for seasonal influenza) | Preparatory Phase |
1. SRM Medical College Hospital and Research Centre, Chennai, 2. KEM Medical College and Hospital, Mumbai, |
| 7 | Zika virus vaccine- Recombinant live attenuated |
Preparatory Phase |
SRM Medical College Hospital and Research Centre, Chennai (proposed) |
| # | Name of Product | Status | Sites |
|---|---|---|---|
| 1 | High-Performance Optical Spectroscopy (HPOS Technology)- Point-of-Care Diagnostic Test for Sickle Cell Anemia | Validation Study Ongoing | 1. NIIH, Mumbai |
| 2 | BP Instrument - Digital Blood pressure measurement using Korotkoff sounds and oscillatory waveforms. | Approved by PRC | 1. Chettinad Hospital and Research Institute, Tamil Nadu 2. RIMS, Ranchi 3. AIIMS, Nagpur |
| 3 | Kit for collection of Dried Blood Spot Samples for the purpose of Therapeutic Drug Monitoring (TDM) of first line AntiTuberculosis Drug Levels (ATT). | Preparatory Phase (Protocol Developed) | 1. AIIMS- Delhi 2. JIPMER, Puducherry |
| 4 | CanScan - a portable, rapid breath analyser test for in-vitro detection of Volatile Organic Compounds (VOCs) associated with breast cancer | Preparatory Phase | 1. AIIMS, Rishikesh 2. Kasturba Medical College, Manipal |
| 5 | SindiColpo - AI based early identification of precervical lesions | Preparatory Phase (Protocol Developed) | 1. Dr. Moopen's Medical College, Wayanad 2. Amrita Institute of Medical Sciences, Kochi |
| 6 | AI based PAP smear - AI-enabled digital pathology system serves as a decision support tool in cervical cancer screening. | Preparatory Phase (Protocol Developed) | 1. AIIMS, Jodhpur 2. SCB Medical College & Hospital, Cuttack |
| 7 | Smart stetho (AISteth) - for screening and diagnostic decision support in cardiovascular conditions | Preparatory Phase (Protocol Developed) | 1. Dr. Moopen's Medical College, Wayanad 2. SRM Medical College Hospital & Research Centre, Chennai |
| 8 | Can Assist - CanAssist Breast (CAB) test is an immunohistochemistry (IHC)-based in vitro diagnostic test performed on invasive breast tumor tissue. | Preparatory Phase | 1. MGMCRI, Puducherry 2. Dayanand Medical College and Hospital, Ludhiana |