• intent@hq.icmr.org.in

The need to build capacity for early-phase clinical trials in India was first identified at a meeting held in 2021 by the Cabinet Secretary of India. This paved the way to building the nation’s first network to conduct early phase clinical trials in order to bridge the gap between pre-clinical research and late phase clinical trials to make India self-reliant as well as the preferred destination for drug development.

Objectives

The ICMR’s initiative to support Phase I clinical trials in India had two main objectives:

  • Establishing Phase I Clinical Trial capacity
  • Funding the leads that have National Health Priority and Readiness for Phase I Clinical Trial.

Existing gaps

  • Leverage public sector funding to derisk translational research.
  • Need for clinical development ecosystem in translational research.
  • Specialized centres required to attract early-phase drug development activity.
  • Complex regulations for translational research.
  • Lack of infrastructure and trained staff.
  • Administrative/ project management support – to ensure efficiency.

ICMR-INTENT

Phase -I Trial Centres

Advanced Centre for Treatment, Research and Education in Cancer ACTREC, Navi Mumbai

Name of PI: Dr. Manjunath Nookala Krishnamurthy

Associate Professor, Scientific Officer F, Dept. of Clinical Pharmacology, ACTREC, Tata Memorial Centre, Navi Mumbai-410210, Maharashtra, India


Details

King Edward Memorial hospital & Seth Gordhandas Sunderdas Medical college (KEMH&GSMC), Mumbai

Name of PI: Dr. Nithya Gogtay

Professor & Head - Department of Clinical Pharmacology KEMH&GSMC Mumbai - 400012, Maharashtra, India

Details
Zoomable Image

Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh

Name of PI: Dr. Nusrat Shafiq

Professor, Clinical Pharmacology Unit, Department of Pharmacology, Postgraduate Institute of Medical Education and Research Chandigarh-160012, India

Details

Sri Ramaswamy Memorial Medical College Hospital and Research Centre (SRM MCH&RC), Chennai

Name of PI: Dr. Satyajit Mohapatra

Director, Centre For Clinical Trials & Research, SRM Medical College Hospital & Research Centre, SRM Nagar, SRM Institute of Science & Technology Kattankulathur-603203 Tamil Nadu, India.

Details

Expected outcomes

  • World class infrastructure supported by ICMR for early phase clinical development of health products.
  • Self-reliance for indigenous early phase clinical development of drugs.